Web31 de mar. de 2024 · Other investigations have corroborated the inhibitory effects of phytochemicals on HIF-1 in control of glucose metabolism. For instance, methylalpinumisoflavone (MF) (PubChem CID: 15596285), a … Web1 de fev. de 2010 · HIF-1 target genes involved in glucose and energy metabolism. HIF-1 activates the transcription of SLC2A1 and SLC2A3, which encode the glucose …
HIF-1 regulates the glucose metabolism. Under well oxygenated ...
Web3 de out. de 2016 · HIF1α is a common component of pathways involved in the control of cellular metabolism and has a role in regulating immune cell effector functions. … Web1 de fev. de 2024 · HIF1 accumulation can be induced by hypoxia, gene mutations, intermediate metabolites, and growth factors. HIF1 plays a pivotal role in lipid … raytracing lumen
HIF-1: upstream and downstream of cancer metabolism.
Web15 de set. de 2024 · Thus, activating HIF in diabetes may provide a mechanism to shift metabolism back toward greater glucose use and suppress fatty acid metabolism, resulting in improved cardiac function . We have previously shown that in diabetes HIF1α stabilization is blunted, and downstream activation of the adaptive hypoxic response is … Web20 de ago. de 2024 · Author summary Accumulating evidence shows that pathogens can affect host metabolism, resulting in human diseases such as obesity and type 2 diabetes. However, how pathogens influence their hosts is still not clear, and this results in a lack of effective and specific clinical treatments. Further investigations into the causes of … Web14 de abr. de 2024 · PKM and LDHA can affect the production and metabolism of pyruvate and lactic acid, thus affecting the citric acid cycle and leading to changes in the concentration of reactive oxygen species, thus activating the HIF-1 signaling pathway . In addition, the SNO modification of GLUD1 was detected in this study, GLUD1 ... ray tracing megakernel