網頁2024年7月5日 · Steatosis is defined as abnormal fat accumulation within hepatocytes, and the minimum criterion for NAFLD diagnosis is the presence of macrovesicular steatosis (a single large fat vacuole... 網頁2024年4月14日 · Hsp70.1 has a dual function as a chaperone protein and lysosomal stabilizer. In 2009, we reported that calpain-mediated cleavage of carbonylated Hsp70.1 causes neuronal death by inducing lysosomal rupture in the hippocampal CA1 neurons of monkeys after transient brain ischemia. Recently, we also reported that consecutive …
The full spectrum of hepatic steatosis in children - PubMed
網頁2024年3月1日 · In the pediatric literature, a prior study of 49 patients (≤18 years) found that a PACS-based measurement of US HRI exhibited excellent diagnostic performance in … 網頁Methods: Information was collected from 155 children with steatosis on liver biopsy, including anthropometrics, laboratory, and radiologic data. Biopsies were reviewed by a … first silver on glass reflectors
NAFLD in children: new genes, new diagnostic modalities and new drugs - Nature
網頁Objectives: To determine the diagnostic accuracy of controlled attenuation parameter (CAP) on FibroScan ® in detecting and grading steatosis in a screening setting and perform a head-to-head comparison with conventional B-mode ultrasound. Methods: Sixty children with severe obesity (median BMI z-score 3.37; median age 13.7 years) were evaluated. 網頁Steatosis or fatty change of fatty liver is the accumulation of abnormal amounts of lipids in 5% or more hepatic cells. Most steatosis is of the macrovesicular type (Fig. 2.10A and … 網頁The aims of our study were: (1) to determine the prevalence of asymptomatic hepatic steatosis and presumed nonalcoholic steatohepatitis, in our local population of obese … first silver age catwoman